Mohs micrographic surgery for deeply penetrating, expanding benign cutaneous neoplasms.

The indications for MMS include malignant tumors with poorly defined borders, histology, tumor size, level of invasion, anatomic location, reduced patient immunity, and recurrence after previous treatment. MMS is indicated for locally aggressive tumors that are difficult to eradicate by routine measures and recurrent tumors following conventional surgical excision. MMS has been used successfully for the excision of basal cell carcinoma, squamous cell carcinoma, squamous cell carcinoma in situ, keratoacanthoma, microcystic adnexal carcinoma, dermatofibroma sarcoma protuberans, and extramammary Paget’s disease. Recent reports have also shown MMS to be successfully used for melanoma, especially the lentigo maligna subtype.